Table 2.

Spearman correlation between biomarkers of oxidative stress and platelet glycoproteins in CF-LVAD patients

Biomarkers of oxidative stress (Baseline to one month)	Platelet glycoproteins (baseline to one month)
	GPIbα Surface	GPIbα Plasma	GPVI Surface	GPVI Plasma
Platelet ROS
Spearman’s ρ	−0.24	0.35	−0.30	0.28
95% confidence intervals (CI)	−0.41 to −0.06	0.18 to 0.50	−0.48 to −0.09	0.11 to 0.44
p-value	0.01*	<0.0001*	0.004*	0.002*
Neutrophil ROS
Spearman’s ρ	−0.54	0.32	−0.20	0.44
95% confidence intervals (CI)	−0.67 to −0.37	0.10 to 0.50	−0.47 to 0.10	0.24 to 0.60
p-value	< 0.0001*	0.004*	0.17	< 0.0001*
Lymphocyte ROS
Spearman’s ρ	−0.32	0.33	−0.09	0.26
95% confidence intervals (CI)	−0.50 to −0.12	0.11 to 0.51	−0.37 to 0.22	0.05 to 0.46
p-value	0.002*	0.003*	0.57	0.02*
Monocyte ROS
Spearman’s ρ	−0.38	0.39	−0.23	0.36
95% confidence intervals (CI)	−0.54 to −0.18	0.19 to 0.56	−0.49 to 0.07	0.15 to 0.53
p-value	0.0002*	0.0002*	0.12	0.001*
SOD
Spearman’s ρ	0.54	−0.51	0.59	−0.57
95% confidence intervals (CI)	0.40 to 0.66	−0.64 to −0.36	0.42 to 0.72	−0.69 to −0.43
p-value	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*
TAC
Spearman’s ρ	0.53	−0.53	0.64	−0.59
95% confidence intervals (CI)	0.39 to 0.65	−0.65 to −0.39	0.49 to 0.75	−0.70 to −0.46
p-value	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*
oxLDL
Spearman’s ρ	−0.57	0.60	−0.63	0.60
95% confidence intervals (CI)	−0.68 to −0.44	0.47 to 0.71	−0.75 to −0.48	0.48 to 0.71
p-value	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*

Note: Result was expressed as ρ (rho) value.

^*statistically significant in spearman’s rank correlation test.