Table 2. Crude and Adjusted Relative Risks and 95% Confidence Intervals for the Association Between Acute Rejection Within 1-Year of Transplantation and ABOi and Select Risk Factors, 2000 to 2015.
Risk factor | Relative risk (95% CI) | Adjusted relative risk (95% CI)1 |
---|---|---|
ABOi | 1.85 (1.62, 2.12) | 1.76 (1.54, 2.01) |
Donor age > 50 y | 1.15 (1.10, 1.20) | 1.23 (1.18, 1.29) |
Recipient age > 50 y | 0.74 (0.71, 0.77) | 0.71 (0.68, 0.74) |
Recipient race | ||
White | Ref | Ref |
Black | 1.16 (1.10, 1.22) | 1.12 (1.06, 1.18) |
Asian | 0.74 (0.66, 0.83) | 0.73 (0.66, 0.82) |
Other/unknown | 0.96 (0.81, 1.13) | 0.97 (0.82, 1.15) |
Maximum PRA > 80% | 1.51 (1.40, 1.63) | 1.51 (1.40, 1.64) |
HLA mismatches ≥ 3 | 1.58 (1.51, 1.66) | 1.60 (1.53, 1.68) |
Previous kidney transplant | 1.14 (1.08, 1.21) | 1.02 (0.99, 1.09) |
Adjusted for recipient race and age at transplant, HLA mismatches GT 3, maximum PRA, previous kidney transplant, and donor age.
ABOi, ABO-incompatible; aRR, adjusted relative risk; HLA, human leukocyte antigen; PRA, panel reactive antibody.