Table 1.
Biomarker† | Baseline level Atorvastatin (N=17) | Change in level Atorvastatin | Baseline level Placebo (N=20) | Change in Level Placebo | t-statistic for treatment effect | P value for treatment effect |
---|---|---|---|---|---|---|
TFPI | 379.91±52.51 | −57.25±16.13 | 387.43±69.89 | 25.40± 21.34 | −3.00 | 0.004 |
CCL24 | 48.60±40.67 | −5.77±3.01 | 62.03±39.80 | 10.14±4.39 | −2.88 | 0.005 |
NT-proBNP | 1.41±0.51 | 0.52±0.24 | 2.27±2.52 | −0.62±0.31 | 2.83 | 0.006 |
MBL2 | 10.32±1.25 | −0.36±0.16 | 11.17±1.16 | 0.17±0.13 | −2.60 | 0.01 |
LTBR | 6.97±3.08 | −0.47±0.40 | 7.61±2.37 | 0.64±0.35 | −2.09 | 0.046 |
PCOLCE | 6.28±0.56 | 0.55±0.10 | 6.78±1.51 | −0.19±0.34 | 1.95 | 0.048 |
TR | 18.28±14.72 | −4.50±2.99 | 16.16±7.91 | 2.33±1.47 | −2.14 | 0.052 |
SELE | 12.92±7.88 | −1.56±1.11 | 11.14±5.10 | 1.00±0.76 | −1.95 | 0.07 |
TNF-R1 | 60.45±27.97 | −5.18±4.75 | 58.04±19.11 | 5.44±2.90 | −1.97 | 0.07 |
CCL16 | 108.91±58.26 | −8.51±6.65 | 120.92±63.94 | 7.00±5.44 | −1.82 | 0.08 |
CHIT1 | 57.03±37.52 | −1.97±4.63 | 48.47±35.12 | 7.31±2.20 | −1.90 | 0.08 |
RETN | 82.63±45.87 | −13.24±9.90 | 75.23±23.07 | 7.95±6.43 | −1.85 | 0.08 |
Results for baseline are Mean ± SD and for change results are Mean ± SEM
For full list of abbreviations, see Supplemental Tables 1 and 2.