Table 1.
Source species | Taxonomy (class and order) | Representative strain | Pathogenicity (Disease) | Polymyxin B MIC (μg/mL)* | Reference |
---|---|---|---|---|---|
Neisseria meningitides | Betaproteobacteria, Neisseriales | MC58 | Pathogen (epidemic meningitis) | ≥512 | [20],[38] |
Neisseria gonorrhoeae | FA 1090 | Pathogen (gonorrhoea) | ≥100 | [20],[38] | |
Escherichia coli | Gammaprotebacteria, Enterobactriales | K-12 MG1655 | Non-pathogenic | 0.25 | [12],[20],[39] |
Shigella flexneri | 2a str. 301 | Opportunistic pathogen (diarrhoea) | 0.5 | [20],[39] | |
Salmonella enterica | subsp. enterica serovar Typhimurium LT2 | Pathogen (gastroenteritis) | 0.5 | [12],[20],[39] | |
Klebsiella pneumoniae | subsp. pneumoniae HS11286 | Pathogen (pneumonia) | ≤0.5 | [12],[39] | |
Pseudomonas aeruginosa | Gammaprotebacteria, Pseudomonadales | PAO1 | Opportunistic pathogen (pneumonia) | 0.5 | [12] |
Acinetobacter baumannii | ATCC 17978 | Pathogen (pneumonia) | 1 | [12] | |
Vibrio cholerae | Gammaprotebacteria, Vibrionaceae | O1 biovar El Tor N16961 | Pathogen (cholera) | >96 | [20],[35] |
Helicobacter pylori | Epsilonproteobacteria, Campylobacterales | 26695 | Pathogen (gastric and duodenal ulcers) | >250 | [20],[36] |
PMB: polymyxin B; MIC: Minimum inhibitory concentration. MICs of Pseudomonas aeruginosa PAO1 and Acinetobacter baumannii ATCC 17978 were based on our unpublished data.