Table 4.
Pearson correlations between Healthy Eating Index-2010 scores and inflammatory cytokines among 42 postmenopausal breast cancer survivors after completion of primary therapy and prior to randomization in a dietary supplement intervention
| Cytokine (pg/mL) | All Participants | Previous Chemotherapy a | No Chemotherapy b | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| N | r | (P-value) | N | r | (P-value) | N | r | (P-value) | ||
| IL-6 c | Unadjusted | 41 | −0.46 | (0.002) | 15 | −0.69 | (0.005) | 26 | −0.29 | (0.15) |
| Adjusted d | −0.26 | (0.10) | −0.67 | (0.009) | −0.02 | (0.93) | ||||
| TNFR-2 e | Unadjusted | 42 | −0.41 | (0.006) | 15 | −0.46 | (0.08) | 27 | −0.37 | (0.06) |
| Adjusted d | −0.30 | (0.06) | −0.59 | (0.03) | −0.19 | (0.35) | ||||
| IL-17 f | Unadjusted | 41 | 0.04 | (0.80) | 14 | 0.03 | (0.91) | 27 | 0.07 | (0.73) |
| Adjusted d | 0.03 | (0.87) | 0.10 | (0.73) | 0.02 | (0.94) | ||||
a
Participants with history of chemotherapy prior to study enrollment
b
Participants without history of chemotherapy prior to study enrollment
c
IL-6, interleukin-6; log transformed due to skewness
d
Linear regression was used to estimate partial correlation, adjusted for body mass index
e
TNFR-2, tumor necrosis factor alpha receptor 2
f
IL-17, interleukin-17; log transformed due to skewness