Table 4.
Mean transcript numbers relative to β-actin per nanogram of RNA of key pyroptotic genes measured by real-time qRT-PCR in the brains of the different mouse groups.
| Mouse group | CASP-1 | IL-1β | IL-18 |
|---|---|---|---|
| DUVV-NL07 i.c. (BALB/c) | 6.42 | 12.8 | 28.8 |
| DUVV-NL07 BPL i.c. (BALB/c) | 0.8 | 1.24 | 12 |
| RABV-PV i.c. (BALB/c) | 6.65 | 20.1 | 19.3 |
| RABV-PV BPL i.c. (BALB/c) | 1.4 | 1.9 | 16.6 |
| DUVV-NL07 i.c. (Swiss) | 7.41 | 6.76 | 10.2 |
| CVS-11 i.c. (Swiss) | 7.24 | 2.04 | 5.9 |
| Controls i.c | 2.04 | 0.76 | 28.8 |
| DUVV-NL07 i.m (BALB/c) | 15.5 | 28.2 | 170 |
| RABV-PV i.m. (BALB/c) | 17.8 | 24.5 | 158 |
| SHBRV-18 i.m. (BALB/c) | 61.7 | 33.1 | 1047 |
| SHBRV-18 i.m. (C57BL/6) | 170 | 38.0 | 302 |
| Controls i.m. | 7.08 | 7.24 | 81 |