Table 2.
Nominal group responses to CDM Question No. 1: Identify scientific and technological innovations that are promising for method development and implementation. Consider reliability, applicability to real world samples, transferability to end users, etc.
| CDM 1 | CDM 2 | Response | ||
|---|---|---|---|---|
| # 1 | S2 | # | S | |
| 3 | 5 | 5 | 16 | Non-toxic solvent (organic) extraction and improvement of extraction methods |
| 2 | 9 | 5 | 18 | Multi-mycotoxin technologies (including IAC (Immunoaffinity Columns)) |
| 2 | 7 | 2 | 5 | Smart phone/on-line transfer of results |
| 1 | 2 | 1 | 4 | Label-free detection or new labels for lateral flow devices |
| ●3 | ● | 3 | 12 | Development of physical methods based on FT-NIR or FT-MIR technology with a database for interpreting results |
| ● | ● | 2 | 7 | MS QqQ (Mass Spectrometry Triple Quadrupole) with internal (isotopically) labeled standards |
| ● | ● | 2 | 4 | Chemically synthesized aptamer probes (based on oligonucleotides) and MIPS, to replace antibody probes |
| 4 | 15 | -4 | - | Miniaturization of MS |
| 3 | 10 | - | - | Reference materials/PT test (Proficiency Test) |
| 3 | 7 | - | - | Improved antibodies, test kits and strips |
| - | - | 3 | 4 | Tool box-like technology for transportability |
| 2 | 7 | - | - | Increased sensitivity/robustness of mass spectrometry |
| - | - | 2 | 7 | Time resolved fluorescent strip method for ppb level analyses |
| 2 | 5 | - | - | Price |
| 1 | 5 | - | - | Association ELISA and app |
| - | - | 1 | 5 | High specificity and affinity recognizers |
| - | - | 1 | 4 | Validated, reliable database for identification of “emerging” mycotoxins by high resolution mass spectrometry |
| 1 | 2 | - | - | LAMP (Loop-mediated isothermal amplification) for detection of fungi |
| - | - | 1 | 2 | Gold nanoparticle-enabled immunoassays (~ppb limit) |
| - | - | 1 | 1 | Non-target screening methods UPLC-MS |
| - | - | 1 | 1 | Microfluidic device exploiting SMART functionalization |
| 1 | 1 | - | - | Alternatives to antibodies |
| ● | ● | - | - | Ambient ionization mass spectrometer |
| - | - | ● | ● | Vibrational spectroscopy methods as “indicators” for fungal degradation |
1 Number of participants ranking this response as one of the five most important. 2 Weighted priority score, with each voting member ranking their top five topics. Five points assigned to the most important response and one point to the least significant of the important responses. 3 This response provided by one or more members of the group when ideas were listed, but was not identified as one of the five most important responses by any member of the group. 4 This response not provided by any member of the group.