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. 2018 Mar 1;10(3):109. doi: 10.3390/toxins10030109

Table 9.

Nominal Group responses to GB Question 4. How can knowledge of fungal gene regulation and biodiversity be applied to the reduction/management of mycotoxin production and the remediation of mycotoxin contaminated materials?

GB 1 GB 2 Response
# 1 S2 # S
7 28 5 20 Use atoxigenic strains (as a biocontrol)
3 7 8 27 RNAi induced gene silencing
6 21 4 8 Identify microbes and enzymes capable of degrading mycotoxins
2 4 3 Competition and interaction with bacteria
-4 - 5 16 Agronomic management to promote beneficial organisms
5 12 - - Modify environmental conditions to inhibit mycotoxin biosynthetic genes
4 13 - - Identify substances that suppress expression of mycotoxin biosynthetic genes
3 11 - - Competition between different species
- - 3 10 Avoid stress (on fungus)
3 8 - - Mycotoxin- mutants as a biocontrol strategy
- - 3 8 Engineered bioremediation/detoxifying organisms
3 7 - - Incorporate knowledge of fungal biodiversity into plant breeding programs
2 7 - - Develop strategy based on knowledge of fungal ecology
- - 2 6 Modeling software
- - 2 6 Impact of chemical control on fungal metabolites
- - 2 4 Biodiversity dynamics: relationship with toxin production and regulation
2 3 - - Use yeast (cell wall) to absorb mycotoxin(s)
- - 2 3 Crop rotation
- - 1 4 Fermentation to reduce toxins
- - 1 4 Biofumigation
- - 1 3 Down regulation of transcription factors
- - 1 1 Toxin production by different species on different host cultivars
- - Apply conditions that suppress mycotoxin synthesis to stored products
- - Improved biocontrol
- - Rapid detection for monitoring by PCR or hybridization
- - Spray-Induced Gene Silencing (SIGS)

1 Number of participants ranking this response as one of the five most important. 2 Weighted priority score, with each voting member ranking their top five topics. Five points assigned to the most important response and one point to the least significant of the important responses. 3 This response provided by one or more members of the group when ideas were listed, but was not identified as one of the five most important responses by any member of the group. 4 This response not provided by any member of the group.