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. 2017 Dec 16;89(4):339–345. doi: 10.1136/jnnp-2017-317134

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This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Correlations between Unified Parkinson’s Disease Rating Scale (UPDRS) and Addenbrooke’s Cognitive Examination (ACE) scores with cytokine levels. (A,B) Correlations between UPDRS and interleukin (IL)-1beta (r=−0.285, P=0.002), IL-2 (r=−0.220, P=0.018) and IL-4 (r=−0.217, P=0.019), and between UPDRS and IL-6 (r=0.208, P=0.025) and tumour necrosis factor (TNF)-alpha (r=0.168, P=0.071). (C,D) Correlations between the ACE score and IL-1beta (r=0.494, P=0.000), IL-2 (r=0.485, P=0.000) and IL-4 (r=0.540, P=0.000), and between the ACE and IL-6 (r=−0.343, P=0.000) and TNF-alpha (r=−0.253, P=0.006).