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. 2017 Nov 3;89(4):374–381. doi: 10.1136/jnnp-2017-316365

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Cross-sectional and longitudinal comparison of fractional anisotropy (FA) values in amyotrophic lateral sclerosis (ALS)-related tract systems. (A) Mean FA values of the baseline scans from 387 patients with ALS and 144 controls for different tract systems and p values for cross-sectional comparison. (B) Longitudinal mean FA decrease slope (ΔFA/d is the slope of FA decrease in units per day) of 67 patients with ALS and 31 controls between baseline and follow-up. Error bars are given as SE of the mean.