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codY mutant cells express thermonuclease (nuc) at early stages of S. aureus biofilm development. S. aureus (UAMS-1) wild-type and codY mutant cells containing the nuc-gfp reporter plasmid pMRSI-nuc were grown in the BioFlux 1000 microfluidic system. Bright-field and epifluorescence microscopic images were acquired at a magnification of ×200 after 6 h of biofilm development. Images are representative of multiple experiments.
