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. 2018 Jan 17;7(3):166–174. doi: 10.1002/psp4.12272

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© 2018 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Interactions among the top 15 gene/protein predictors. Interactions among the top 15 genes/proteins selected by our model to best predict cardiomyopathy using cardiomyocytes data are depicted as a network using the STITCH website for visualization. Small nodes correspond to protein of unknown 3D structure and large nodes to known or predicted. Edges represent protein‐protein associations and the intensity of the line is proportional to the confidence score of each association. The confidence score is calculated by combining the probabilities from all evidence channels and is corrected for random observation probability.