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. 2018 Mar 27;8:5239. doi: 10.1038/s41598-018-23575-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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A schematic of Rheb evolution in the SAR clade. The figure shows the most parsimonious interpretation of the taxonomic distribution, sequence features, and phylogenetic relationship of Rheb proteins in the group. The phylogenetic relationships of the taxa are depicted based on the most recent molecular phylogenetic and phylogenomic analyses. Relationships of the taxa are based on refs^33,62,63. Species representing the broader clades indicated in the tree are listed in Supplementary Table S1.