Table 3.
Comparison of amperometric response of varieties of nanoporous gold (np-Au)-based glucose biosensors.
| Electrode | Rf | Potential a | Mediator | Linear (mM) | LOD (µM) | Sensitivity (µA·cm−2·mM−1) |
Ref. |
|---|---|---|---|---|---|---|---|
| GOx-Chi/PB/np-Au/Ti | NA | −1.0 V b | PB | 0.1–2.0 | 2.5 | 177 c | [119] |
| Naf/GOx/np-Au/GC | NA | 0.4 V | - | 1–18 | 196 | 0.049 c | [30] |
| GOx/SAM/np-Au/GC | NA | −0.2 V b | - | 3–8 | 10 | 8.6 | [110] |
| Naf/GOx/PB/np-Au/Cr/Si | 40 | 0 V b | PB | 2–30 | 300 | 50 | [120] |
| GOx/Os(bpy)2P/np-Au/SiO2 | NA | NA | Os(bpy)2P | NA | 2 | 75 | [121] |
| GOx/PEDOT/np-Au/GC | NA | 0.2 V | BQ | 0.1–15 | 10 | 7.3 | [122] |
| GOx/np-Au/Au/Si | 36 | NA | - | 0.1–0.5 | 73 | 21.14 | [123] |
| GOx/GA/CA/np-Au/GC | 7 | 0.2 V 0.3 V |
BQ FCA |
1–10 1–10 |
NA NA |
3.53 1.35 |
[124] |
| GOx/DTDPA/np-Au/GC | 8 | 0.2 V | BQ | 1–10 | NA | 2.187 | [9] |
| GOx/np-Au/GC | 8 | 0.3 V | - | 0.05–10 | 1.02 | 12.1 | [125] |
a vs. SCE, b vs. Ag/AgCl, c µA·mM−1, Rf: roughness factor of np-Au, Chi: chitosan, GC: glassy carbon electrode, Naf: Nafion, PB: Prussian blue (ferric hexacyanoferrate), DET: direct electron transfer, BQ: p-benzoquinone, FCA: ferrocenecarboxylic acid, GA: glutaraldehyde, CA: cysteamine, DTDPA: 3,3′-Dithiodipropionic acid, PEDOT: poly(3,4-ethylenedioxythiophene), Os(bpy)2P: [Os(2,2′-bipyridine)2(polyvinylimidazole)Cl]+/2+.