Table 1.

Clinical and histopathological characteristics of the LNN patients.

		N (%)	miR-320	P value	miR-221	P value	miR-30b	P value		P value	miR-885– 5p	P value	let-7i	P value
Gender	Female	73 (47.1%)	−4.50(−5.01–4.10)	0.94	−1.78(−2.56–1.18)	0.42	−1.79(−2.37–1.27)	0.025	−2.55(−3.12–1.80)	0.09	−11.20(−13.00–10.32)	0.96	−2.97(−3.45–2.28)	0.14
	Male	82 (52.9%)	−4.55(−4.97–3.99)		−1.77(−2.39–0.97)		−1.59(−1.99–1.14)		−2.68(−3.18–2.15)		−11.39(−12.74–10.48)		−3.16(−3.87–2.48)
Age		155 (100%)	−0.05	0.57	−0.13	0.10	0.01	0.87	0.09	0.25	0.02	0.78	0.07	0.39
Tumour stage	Stage I	57 (36.8%)	−4.61(−5.01–4.03)	1.00	−1.78(−2.45–0.88)	0.65	−1.55(−1.97–1.07)	0.13	−2.62(−3.29–1.90)	0.96	−11.21(−12.88–10.09)	0.16	−2.59(−3.55–2.09)	0.037
	Stage II	98 (63.2%)	−4.49(−4.99–4.08)		−1.77(−2.51–1.16)		−1.75(−2.17–1.35)		−2.66(−3.13–2.02)		−11.39(−13.00–10.52)		−3.15(−3.61–2.66)
T status	T2	57 (36.8%)	−4.61(−5.01–4.03)	1.00	−1.78(−2.45–0.88)	0.65	−1.55(−1.97–1.07)	0.13	−2.62(−3.29–1.90)	0.96	−11.21(−12.88–10.09)	0.16	−2.59(−3.55–2.09)	0.037
	T3	98 (63.2%)	−4.49(−4.99–4.08)		−1.77(−2.51–1.16)		−1.75(−2.17–1.35)		−2.66(−3.13–2.02)		−11.39(−13.00–10.52)		−3.15(−3.61–2.66)
Nodal status	N0	127 (81.9%)	−4.47(−4.95–4.01)	0.23	−1.77(−2.51–1.13)	0.72	−1.75(−2.13–1.32)	0.053	−2.61(−3.11–1.91)	0.15	−11.34(−13.00–10.48)	0.56	−3.05(−3.54–2.38)	0.48
	N0 < 10 nodes	28 (18.1%)	−4.72(−5.14–4.13)		−1.71(−2.46–0.67)		−1.40(−1.99–0.91)		−2.73(−3.37–2.06)		−11.28(−12.94–9.50)		−3.12(−3.96–2.36)
Tumour grade	Good	13 (8.4%)	−4.38(−4.91–3.99)	0.77	−1.59(−1.97–1.06)	0.21	−1.54(−1.95–1.26)	0.95	−2.74(−3.29–1.89)	0.98	−11.61(−13.00–10.50)	0.28	−3.01(−3.86–2.39)	0.51
	Moderate	130 (83.9%)	−4.52(−5.02–4.03)		−1.82(−2.50–1.14)		−1.74(−2.13–1.26)		−2.65(−3.13–1.95)		−11.32(−13.00–10.43)		−3.12(−3.56–2.36)
	Poor	9 (5.8%)	−4.58(−5.41–4.22)		−2.35(−3.58–1.21)		−1.73(−2.58–1.01)		−3.00(−3.27–2.31)		−11.64(−12.91–10.60)		−2.87(−3.66–2.44)
	Other	3 (1.9%)	−4.27(−4.71–)		−1.77(−2.16–)		−1.08(−1.52–)		−1.59(−2.26–)		−9.15(−10.49–)		−2.55(−3.00–)
Location	Right	79 (51.0%)	−4.49(−4.88–4.09)	0.76	−2.16(−2.69–1.47)	0.001	−1.82(−2.16–1.46)	0.029	−2.49(−2.77–1.78)	<0.001	−11.22(−13.00–10.41)	0.70	−3.16(−3.59–2.37)	0.55
	Left	76 (49.0%	−4.58(−5.11–4.02)		−1.48(−2.19–1.09)		−1.56(−1.97–1.09)		−2.94(−3.41–2.29)		−11.35(−12.79–10.45)		−3.03(−3.54–2.44)
MSI-status a	MSI	34 (22.1%)	−4.50(−4.80–4.00)	0.44	−2.53(−3.06–2.10)	<0.001	−2.00(−2.20–1.60)	0.007	−2.12(−2.63–1.45)	<0.001	−12.33(−13.00–10.58)	0.011	−3.01(−3.34–2.46)	0.50
	MSS	120 (77.9%)	−4.51(−5.08–4.05)		−1.61(−2.30–0.94)		−1.61(−1.99–1.15)		−2.73(−3.24–2.12)		−11.21(−12.65–10.26)		−3.08(−3.68–2.35)

Data are given as median (interquartile range). ^aOne missing value.