Table 1.
Characteristics of study participants according to uric acid tertile (mg/dl).
| 1st tertile < 5.0 | 2nd tertile 5.0–6.1 | 3rd tertile > 6.1 | p value | |
|---|---|---|---|---|
| (n = 313) | (n = 307) | (n = 353) | ||
| Framingham CVD risk score (%) | 8.8 ± 8.5 | 14.2 ± 11.7 | 20.4 ± 14.4 | <0.001 |
| Framingham CVD risk score components | ||||
| Age (years) | 60 ± 8.0 | 62 ± 8.0 | 63 ± 9.0 | 0.005 |
| Male, n (%) | 55 (17.6) | 136 (44.3) | 264 (74.8) | <0.001 |
| HDL-C (mg/dl) | 62 ± 14 | 56 ± 13 | 52 ± 13 | <0.001 |
| Total cholesterol (mg/dl) | 200 ± 34 | 201 ± 34 | 202 ± 36 | 0.878 |
| SBP (mmHg) | 122 ± 15 | 125 ± 16 | 128 ± 16 | 0.002 |
| Smoking | 38 (12.1) | 100 (32.4) | 171 (48.4) | <0.001 |
| Covariates | ||||
| BMI (kg/m2) | 23 ± 3.0 | 24 ± 3.2 | 25.0 ± 3.0 | <0.001 |
| LDL-C (mg/dl) | 118 ± 31 | 125 ± 30 | 126 ± 33 | <0.001 |
| Triglycerides (mg/dl) | 96 ± 51 | 110 ± 57 | 139 ± 89 | <0.001 |
| HbA1c (%) | 5.8 ± 0.7 | 5.8 ± 0.6 | 5.7 ± 0.5 | 0.189 |
| cIMT (mm) | 0.63 ± 0.11 | 0.67 ± 0.14 | 0.68 ± 0.13 | <0.001 |
| hsCRP (mg/dl) | 0.16 ± 0.32 | 0.21 ± 0.56 | 0.21 ± 0.36 | 0.004 |
| Uric acid (mg/dl) | 4.2 ± 0.6 | 5.5 ± 0.3 | 7.2 ± 1.0 | <0.001 |
Values are mean ± standard deviation or n (%). BMI = body mass index, cIMT = carotid intima–media thickness, CVD = cardiovascular disease, HbA1c = glycated hemoglobin, HDL-C = high-density lipoprotein cholesterol, hsCRP = high-sensitivity C-reactive protein, LDL-C = low-density lipoprotein cholesterol, SBP = systolic blood pressure.