Table 3.
Demographic and clinical characteristics by aortic calcification score categories for the ERA-JUMP Study, 2002–2006 (n = 1006).
| AoCaS categories | AoCaS=0 | AoCaS 1-99 | AoCaS 100-299 | AoCaS ≥300 | p-trendd |
|---|---|---|---|---|---|
| Total number (%) | 434 (43.1) | 372 (37.0) | 91 (9.1) | 109 (10.8) | – |
| Agea, years | 44.9 (0.1) | 45.4 (0.2) | 46.2 (0.3) | 46.3 (0.3) | 0.01/0.27 |
| BMIa, kg/m2 | 26.2 (0.3) | 28.8 (0.3) | 28.9 (0.5) | 27.4 (0.4) | 0.01/0.01 |
| Pack-years of smokingb | 0.0 (0.0, 0.9) | 0.0 (0.0, 1.2) | 0.0 (0.0, 13.6) | 11 (0.0, 19.7) | 0.01/0.01 |
| Alcoholb, gm/day | 5.0 (1.0, 15.9) | 3.7 (1.0, 13.6) | 3.4 (1.0, 11.5) | 22.9 (2.1, 35.0) | 0.01/0.01 |
| LDL-Ca, mg/dl | 130.5 (2.6) | 137.8 (2.3) | 131.8 (4.1) | 137.9 (3.8) | 0.18/0.83 |
| HDL-Ca, mg/dl | 50.3 (1.0) | 46.4 (0.9) | 46.0 (1.5) | 49.6 (1.4) | 0.62/0.01 |
| Triglyceridesb, mg/dl | 115.1 (80.7, 156.8) | 130.1 (95.7, 185.5) | 149.4 (104.7, 209.0) | 134.3 (94.7, 239.0) | 0.01/0.03 |
| Hypertensionc | 43 (9.9) | 60 (16.1) | 19 (20.7) | 18 (16.0) | 0.01/0.02 |
| Diabetesc | 10 (2.3) | 11 (2.9) | 7 (7.3) | 6 (5.3) | 0.01/0.25 |
| Anti-lipid medc | 39 (9.0) | 40 (10.8) | 24 (26.1) | 16 (14.3) | 0.01/0.03 |
| Meat intakec | 325 (74.9) | 290 (78.0) | 74 (80.6) | 83 (75.9) | 0.70/0.25 |
| Years of educationb | 17.0 (16.0, 18.0) | 17.0 (16.0, 18.0) | 16.0 (16.0, 18.0) | 16.0 (16.0, 18.0) | 0.01/1.00 |
| CRPb, mg/dl | 0.81 (0.42, 1.60) | 1.04 (0.55, 1.84) | 0.99 (0.53, 2.17) | 1.03 (0.49, 1.94) | 0.04/0.17 |
| Fibrinogena, mg/dl | 284.7 (5.2) | 293.0 (4.8) | 300.4 (8.1) | 299.1 (7.6) | 0.04/0.40 |
AoCaS, aortic calcification score; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; CRP, C-reactive protein.
Values for all variables except age were adjusted for ‘age’ and ‘race/ethnicity’: Value of age was fixed at 45.3 years and race was fixed as ‘US White’.
Continuous normally distributed variables were expressed as mean (standard error).
Continuous non-normally distributed variables were expressed as median (inter-quartile range).
Categorical variables were expressed as numbers (%).
p-trend shows p-values for linear and quadratic trends across the aortic calcification score categories.
SI conversion factors: To convert LDL-C and HDL-C to mmol/L, multiply values by 0.0259. To convert triglycerides to mmol/L, multiply values by 0.01129. To convert fibrinogen to μmol/L, multiply values by 0.0294. To convert CRP to nmol/L, multiply values by 9.524.