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Risk stratification for AIP mutations, classified as low risk (<5%), moderate risk (5%–19%) or high risk (≥20%). Red: risk of AIP mutation ≥20%; orange: risk of AIP mutation between 5% and 19%; green: risk of AIP mutation <5%. GH, growth hormone; macro, macroadenoma; micro, microadenoma; simplex, patients with no known family history.
