Table 1.

Clinical characteristics of the whole cohort

Clinical characteristic	n=1405*
AIP mutation, n (%)	134 (9.5)
Familial, n (%)	607 (43.2)
Gender, n (% male)	680 (48.5)
Diagnosis, n (%)
GH excess	767 (55.5)
NFPA	185 (13.4)
Prolactinoma	344 (24.9)
Cushing’s disease	74 (5.4)
Other diagnosis	11 (0.8)
Age of onset (years)	27.1±13.1
Age at diagnosis (years)	30.8±13.4
Macroadenoma, n (%)	977 (81.5)
Extrasellar extension, n (%)	446 (60.1)
Pituitary apoplexy, n (%)	48 (3.9)

*Prospectively diagnosed patients excluded.

NFPA, non-functioning pituitary adenoma.