Table 1. Comparison of demographics and clinical features amongst the patients in different groups.
| Variable | Groups | Χ2 | ||||||
|---|---|---|---|---|---|---|---|---|
| Healthy (%) | Cognitive impairment (%) | |||||||
| Adult | Elderly | Advanced age | Va-MCI | VaD | Ad-MCI | AdD | ||
| Number of subjects | 15 | 12 | 24 | 6 | 9 | 8 | 18 | |
| Age (years) | 42.7 ± 13.8 | 78.2 ± 6.4 | 90.0 ± 2.6 | 93.7 ± 4.7 | 91.4 ± 5.4 | 90.2 ± 4.9 | 89.44 ± 4.5 | 32.2ΔΔ |
| Gender | N | |||||||
| Male | 15 (100.0) | 12 (100.0) | 24 (100.0) | 6 (100.0) | 9 (100.0) | 8 (100.0) | 18 (100.0) | |
| Female | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Blood/plasma transfusion | 8.996 | |||||||
| No | 15 (100.0) | 12 (100.0) | 24 (100.0) | 5 (83.3) | 9 (100.0) | 8 (100.0) | 16 (88.9) | |
| Yes | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (16.7) | 0 (0.0) | 0 (0.0) | 2 (11.1) | |
| Administered human albumin | 8.830 | |||||||
| No | 15 (100.0) | 12 (100.0) | 22 (92.0) | 4 (66.7) | 7 (77.8) | 7 (87.5) | 14 (77.8) | |
| Yes | 0 (0.0) | 0 (0.0) | 2 (8.0) | 2 (33.3) | 2 (22.2) | 1 (12.5) | 4 (22.2) | |
| Taking deproteinated calf blood jelly | 9.846 | |||||||
| No | 15 (100.0) | 12 (100.0) | 24 (100.0) | 5 (83.3) | 8 (88.9) | 8 (100.0) | 15 (83.3) | |
| Yes | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (16.7) | 1 (11.1) | 0 (0.0) | 3 (16.7) | |
| Mid-value of detected indexes | ||||||||
| GDF-11 (pg/ml) | 25.96 | 21.40 | 30.32 | 101.08 | 33.95 | 17.62 | 23.95 | 9.668 |
| β2-MG (mg/dl) | 0.160 | 0.255 | 0.295 | 0.325 | 0.450 | 0.315 | 0.390 | 34.661ΔΔ |
ΔΔ, between-group comparison P<0.01; N, not determined.