Table 1.
Clinicopathological variables | Frequency n (%) | Disease-free survival | p value | Overall survival | p value |
---|---|---|---|---|---|
5-year survival rate (%) | 5-year survival rate (%) | ||||
Tumor site | |||||
Proximal | 95 (32.6) | 36.1 | 0.001 | 39.3 | 0.002 |
Body | 65 (22.3) | 65.9 | 65.9 | ||
Distal | 131 (45.0) | 62.6 | 65.9 | ||
< 15 | 157 (54.0) | 56.0 | 57.8 | ||
T stage | |||||
1 | 66 (23.0) | 89.6 | < 0.001 | 89.6 | < 0.001 |
2 | 27 (9.3) | 78.6 | 85.7 | ||
3 | 105 (36.1) | 49.3 | 52.2 | ||
4 | 92 (31.6) | 30.8 | 33.8 | ||
N stage | |||||
0 | 131 (45.0) | 73.7 | < 0.001 | 75.8 | < 0.001 |
1 | 63 (21.6) | 55.6 | 58.3 | ||
2 | 52 (17.9) | 27.3 | 30.3 | ||
3 | 45 (15.5) | 21.4 | 25.0 | ||
Tumor stage | |||||
I | 79 (27.1) | 90.4 | < 0.001 | 90.4 | < 0.001 |
II | 92 (31.6) | 59.4 | 65.2 | ||
III | 120 (41.2) | 25.0 | 26.4 | ||
Differentiation | |||||
Well/moderate | 150 (51.5) | 62.3 | 0.029 | 65.1 | 0.022 |
Poor | 141 (48.5) | 46.7 | 48.9 | ||
Vascular invasion | |||||
No | 168 (57.2) | 65.9 | < 0.001 | 68.2 | < 0.001 |
Yes | 123 (42.3) | 32.8 | 35.9 | ||
Lymph node ratio | |||||
0 | 131 (45.0) | 73.7 | < 0.001 | 75.8 | < 0.001 |
0.01–0.24 | 75 (25.8) | 53.2 | 55.3 | ||
0.25–0.49 | 54 (18.6) | 20.0 | 23.3 | ||
≥ 0.50 | 31 (10.7) | 20.0 | 25.0 | ||
Lymph node sample | |||||
≥ 15 | 134 (46.0) | 54.0 | 0.786 | 57.5 | 0.963 |
R status | |||||
0 | 246 (84.5) | 61.0 | < 0.001 | 64.0 | < 0.001 |
1 | 45 (15.5) | 12.5 | 12.5 | ||
Adjuvant chemotherapy | |||||
No | 230 (79.0) | 69.9% | 0.725 | 60.8% | 0.147 |
Yes | 61 (21.0) | 66.7% | 46.7% | ||
Neoadjuvant therapy | |||||
No | 246 (84.5) | 56.3 | 0.338 | 59.1 | 0.227 |
Yes | 45 (15.5) | 45.0 | 45.0 |