Table 3.
Cognitive Functioning Tests: Comparisons of Screening vs Predoses (ITT Analysis Set)
| Tests | ||
|---|---|---|
| Screening | Predose Period 1 | |
| N | 24 | 24 |
| Detection | ||
| Mean (SD) | 2.40 (0.051) | 2.41 (0.062) |
| p valuea | 0.329 | |
| Identification | ||
| Mean (SD) | 2.61 (0.047) | 2.61 (0.042) |
| p value | 0.482 | |
| One-Card Learning | ||
| Mean (SD) | 1.09 (0.125) | 1.08 (0.120) |
| p value | 0.849 | |
| One Back Memory | ||
| Mean (SD) | 2.76 (0.072) | 2.76 (0.086) |
| p value | 0.697 | |
| Groton Maze Learning Test | ||
| Mean (SD) | 38.42 (9.117) | 37.00 (14.200) |
| p value | 0.567 |
p value – predose vs screening
Detection - speed of performance (Log10 ms), Identification - speed of performance (Log10 ms), One-Card learning - accuracy of performance, One Back memory - speed of performance (Log10 ms), Groton Maze learning test - total numbers of errors, ms – milliseconds
ap values (2-sided with level of significance of 5%) and CIs (2-sided) are based on paired t-test