Table 1.
Passive electrophysiological properties of pyramidal and gabaergic interneurons in the agranular RSC
| n | Age (days) | Distance to pia (µm) | V rest (mV) | R m (peak) (MΩ) | V sag | τ m (ms) | |
|---|---|---|---|---|---|---|---|
| Pyr 2/3 | 23 | 19.2 ± 1.1 | 190.6 ± 33.0 | − 75.5 ± 4.1 | 166.4 ± 55.0 | 0.04 ± 0.03 | 22.6 ± 7.7 |
| Pyr 5m | 25 | 19.9 ± 1.4 | 396.0 ± 71.5 | − 65.2 ± 5.4 | 211.7 ± 67.6 | 0.11 ± 0.06 | 21 ± 4.9 |
| Pyr 5BL | 21 | 19.4 ± 0.9 | 547.2 ± 71.1 | − 65.7 ± 2.2 | 46.9 ± 13.2 | 0.25 ± 0.04 | 11.8 ± 2.0 |
| Pyr 6 | 17 | 19.5 ± 0.8 | 941.6 ± 114.5 | − 72.7 ± 5.2 | 215.0 ± 62.7 | 0.16 ± 0.05 | 15.9 ± 4.1 |
| PV-FS | 45 | 19.7 ± 1.2 | 452.7 ± 217.7 | − 72.1 ± 5.1 | 70.8 ± 24.0 | 0.10 ± 0.04 | 5.9 ± 1.9 |
| Non PV-FS | 16 | 19.2 ± 1.3 | 359.7 ± 206.5 | − 73.0 ± 2.8 | 196.7 ± 81.5 | 9.2 ± 5.4 |
Resting membrane potential (V rest) was measured as the average potential of a 5 s time window after going into whole cell configuration; membrane input resistance (R m) was computed from the slope of the linear fit from steady state voltage responses to low amplitude hyperpolarizing current square steps; membrane time constant (τ m) was estimated form the voltage response to a hyperpolarizing current step < 50 pA; voltage sag ratio (V sag) was calculated from the voltage response to a – 300 pA square current injection of 1 s as the ratio between the steady state and peak membrane potential. The Pyr 5m group includes 5A and 5Bm pyramidal neurons. Data are shown as mean ± SD