Table 3.
Spatial relationship between CaV2.1 or GIRK2 and GABAB1 clusters
| Clusters | Compartment | Inter-cluster distance | N |
|---|---|---|---|
| GIRK2 to GABAB1 | Active zone | 84.2 ± 46.1 | 21 |
| Dendrite | 219.6 ± 119.0 | 54 | |
| Spine | 110.7 ± 73.4 | 100 | |
| CaV2.1 to GABAB1 | Active zone | 68.5 ± 45.1 | 44 |
| Dendrite | 124.2 ± 126.7 | 85 | |
| Spine | 154.9 ± 85.9 | 31 |
Inter-cluster distances from CaV2.1 or GIRK2 clusters to the nearest neighbouring GABAB1 clusters are reported as mean ± standard deviation. Inter-cluster distances between GIRK2 and GABAB1 in dendritic shafts differed significantly from both the ones in spines (p < 0.001) and in active zones (p < 0.001), while there was no significant difference between inter-cluster distances in spines and active zones (p = 0.12). Inter-cluster distances between CaV2.1 and GABAB1 were showed significant differences between active zones and dendritic shafts (p = 0.004), active zones and dendritic spines (p < 0.001) as well as dendritic shafts and spines (p = 0.009). p values were obtained by Mann–Whitney U test followed by Holm–Bonferroni correction. N indicates the number of CaV2.1 or GIRK clusters analysed