Fig. 9.

BAI prevents synaptic loss in MHE rats and DA-treated rats. a–f Immunoblot analysis and subsequent densitometry of hippocampal (a–c) and cortical (d–f) lysates from MHE or DA-treated rats administered various concentrations of BAI (20, 50, 100 mg/kg) using anti-PSD95/synapsin I and anti-β-actin antibodies. g Double immunofluorescence staining of hippocampal sections from MHE or DA-treated rats administered BAI (100 mg/kg) using antibodies against PSD95 (red), MAP2 (green). (h, i) Double immunofluorescence staining of cortical sections from MHE or DA-treated rats administered BAI (100 mg/kg) using antibodies against PSD95 (h)/synapsin I (i) (red), MAP2 (green). *P < 0.05, **P < 0.01 vs. MHE rats; #P < 0.05, ##P < 0.01 vs. DA-treated rats. Scale bar, 25 μm. MRGD, merged image