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. 2018 Jan 31;9:98–113. doi: 10.1016/j.molmet.2018.01.009

Figure 5.

Figure 5

Echocardiography analysis. (A) Representative echocardiography analysis in 6 month-old Cc1+/+ (white bar), Cc1−/− (black bar) and Cc1−/−xliver+ mice (gray bar) (n = 10/genotype). Septal wall thickness at end diastole (SWTd) (i), posterior wall thickness at end diastole (PWTd) (ii), fractional shortening (FS) (iii), myocardial performance index (MPI) (iv) were determined. Values are expressed as mean ± SEM. *P ≤ 0.05 versus Cc1+/+ and †P ≤ 0.05 Cc1−/−xliver+ versus Cc1−/− mice. (B) (i) Representative M-mode of each mouse type demonstrating cardiac hypertrophy and reduced wall motion of Cc1−/− mice. Cc1−/−xliver+ mice manifest normal LV geometry and function.