Figure 4.

SIN decreased Nox2 expression in rat lung tissues. (A) Protein level of Nox2 in the lung tissues of rats from different groups was measured by Western blot assay; (B) Relative Nox2 mRNA level in the lung tissues of rats from different groups was measured by qRT-PCR. Con – Control group (rats exposed to normoxia); Con-S – rats with normoxia exposure + sinomenine administration 41 μg kg⁻¹∙min⁻¹ for 25 days; CIH – rats exposed to CIH alone; CIH-S – rats with CIH exposure + sinomenine administration at 41 μg kg⁻¹∙min⁻¹ for 25 days. Data are reported as means ±SE. *, ** p<0.05, 0.01 vs. control; ^# p<0.05 vs. CIH.