Skip to main content
. 2018 Jan 31;9:84–97. doi: 10.1016/j.molmet.2018.01.016

Figure 4.

Figure 4

Electrical activity and VDCC currents in WT and TALK-1 KO δ-cells. (A) Vm recording from a WT δ-cell treated with indicated glucose concentrations (representative of recordings obtained from N = 12 cells/4 mice per genotype). (B) Vm recording from a TALK-1 KO δ-cell treated with indicated glucose concentrations (representative of recordings obtained from N = 12 cells/4 mice per genotype). (C) Quantification of plateau fraction in WT and TALK-1 KO δ-cells (N = 12 cells/4 mice per genotype). (D and E) Average Vm in WT and TALK-1 δ-cells at 1 and 11 mM glucose. (N = 12 cells/4 mice per genotype). (F) VDCC currents recorded from WT (representative of N = 9 cells/3 mice per genotype) and TALK-1 KO (representative of N = 8 cells/3 mice per genotype) δ-cells. VDCC current densities are quantified in (G); *P < 0.05.