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. 2017 Nov 16;9(4):841–849. doi: 10.1039/c7sc03712k

Table 2. Mutation frequency (M. F.) induced by treatment with Ru1 or cisplatin, as determined by HPRT-forward mutation assay in V79 Chinese hamster cells a .

M.F. b Rel. M.F. c
Control 6.3 ± 2.4 1.0
Ru1 36.7 ± 7.3 5.8
Cisplatin 65.5 ± 11.3 10.4

aCells were treated with 2 μM of each complex for 24 h.

b6-TG resistant mutations per 1 × 105 viable cells.

cRatio of induced to spontaneous mutations.