Table 3.
Distribution of the genotypes, allele’s frequencies and odd ratio of the ADRB1 Arg389Gly polymorphism in control, overweight and obese subjects
| Genotype | Control T = 115 |
Overweight T = 68 |
Obese T = 146 |
χ2 Odds ratio (95% CI) | P- value |
|---|---|---|---|---|---|
| Genotype Frequency | |||||
| Arg\Arg | 20 (17.4) | 12 (17.6) | 18 (12.3) | χ2 Ow = 0.08 Ob = 0.7 -Odds ratio (95% CI) Control vs OW 1.09(0.6–1.9) -Odds ratio (95% CI) Control vs Obese 1.2(0.75–1.3) |
P value for Odds ratio in control vs overweight: 0.8 and control vs obese:0.4 |
| Arg\Gly | 45 (39.1) | 25 (36.8) | 57 (39) | ||
| Gly\Gly | 50 (43.5) | 31 (45.6 | 71 (48.6) | ||
| Allele Frequency | |||||
| Allele Arg389 | 37.0% | 36% | 31.8% |
Odds ratio (95% CI) Control vs OW 1.04 (0.67–1.6) Odds ratio (95% CI) Control vs Obese1.25(0.9–1.8) |
P = 0.86 |
| Allele Gly 389 | 63.o% | 64% | 68.2% | P = 0.22 | |
OW = Overweight; Ob = Obese; CI: Confidence interval; χ2: Chi square