Table 5.
The genotypes and allele frequencies of ADRB3 Trp64Arg polymorphism in control, overweight and obese subjects
| Genotype |
Control
T = 115 |
Overweight
T = 68 |
Obese
T = 146 |
χ 2 Odds ratio (95% CI) | P- value |
|---|---|---|---|---|---|
| Genotype Frequency | |||||
| Trp\Trp | 112 (97.4) | 61 (89.7) | 116 (79.5) |
χ
2
OW = 4.9 Ob = 12.4 Odds ratio (95% CI) Control vs OW 4.3 (1–17) Odds ratio (95% CI) Control vs Obese 7 (2–24) |
P value for Odds ratio in normal vs overweight 0.02 and normal vs obese: 0.0004 |
| Trp\Arg | 3 (2.6) | 7 (10.3) | 23 (15.8) | ||
| Arg\Arg | 0 | 0 | 7 (4.8) | ||
| Allele Frequency | |||||
| Trp64 | 98.7% | 94.9% | 87.3% |
Odds ratio (95% CI) Control vs OW 4.11 (1.04–16.1) Odds ratio (95% CI) Control vs Obese 10.98 (3–36) |
P = 0.02 |
| Arg64 | 1.3% | 5.1% | 12.7% | P = 0.00001 | |
OW = Overweight; Ob = Obese; CI: Confidence interval; χ2 = Chi square