Table 6.
Phenotypic Characteristics of subjects grouped according to ADRB3 polymorphism at Codon 64
| Phenotypic variables | Trp64Trp64 (n = 289) mean ± SE |
Trp64Arg64 (n = 33) mean ± SE |
Arg64Arg64 (n = 7) mean ± SE |
P-value |
|---|---|---|---|---|
| BMI (kg/m2) | 27.640± 0.402 | 32.48± 6.36 | 45.4± 1.8 | 0.0001 |
| Waist(cm) | 86.51± 1.06 | 98.24± 2.95 | 119.14 ± 4.83 | 0.0001 |
| Hip(cm) | 106.82± 0.88 | 112.18± 2.55 | 129.57± 3.72 | 0.0001 |
| W/H ratio | 0.81 ± 0.01 | 0.87 ± 0.02 | 0.92 ± 0.04 | 0.0001 |
| Cholesterol (mmol/L) | 3.94± 0.05 | 4.36± 0.165 | 5.63± 0.32 | 0.0001 |
| Triglyceride (mmol/L) | 1.02± 0.03 | 1.31± 0.09 | 1.643± 0.181 | 0.0001 |
| HDL (mmol/L) | 1.193 ± 0.02 | 1.12± 0.05 | 1.08± 0.120 | 0.335 |
| LDL (mmol/L) | 2.051± 0.045 | 2.319± 0.147 | 3.286± 0.244 | 0.0001 |
| Leptin (ng/ml) | 21.95± 1.063 | 24.38± 2.52 | 57.14± 10.74 | 0.0001 |
| Fasting Insulin (pmol/L) | 79.018± 2.24 | 101.6± 6.88 | 111.70± 17.37 | 0.001 |
| Fasting Glucose(mmol/L) | 4.903± 0.030 | 5.234± 0.12 | 4.89± 0.06 | 0.003 |
Values are mean ± SEM. Abbreviations: BMI, body mass index; W/H, waist hip ratio