Table 2.

Number of recurrence for patients with high or low TOP2A expression according to site and time of recurrence

	All patients	TOP2A protein expression
		High	Low	P value
	n = 434	n = 127	n = 307
All recurrence n (%)	47(10.8)	21(16.5)	26 (8.5)	0.018
Site of recurrencea n (%)
Distant	38(8.8)	18 (14.2)	20 (6.5)	0.015
Locoregional	11 (2.5)	4 (3.1)	7 (2.3)	0.737
Time of recurrence n (%)
0–5	31 (7.1)	12 (9.4)	17 (6.2)	0.213
5–8	16 (3.7)	9 (7.1)	7(2.3)	0.021

^aThere were two patients had both locoregional and distant recurrence