Table 3.

Description of included studies

Category	Type of intervention and comparison	Study ID	Participants	Follow-up duration	Study location	Outcomes
Adherence support	Home-based nursing vs. standard care	Berrien 2004 [23]	HIV-positive children. N = 37.	12 months.	Connecticut, USA.	Adherence; Viral load; CD4 count.
		Wang 2010 [28]	HIV-positive adults; active or previous heroin addicts; on ART at least 1 month prior to starting study. N = 116.	10 months.	Hunan, China.	Adherence.
		Williams 2006 [27]	HIV-positive adults on ART. N = 171.	15 months.	Connecticut, USA.	Adherence; Viral load; CD4 count.
		Williams 2014 [29]	HIV-positive adults; on ART; self-reported < 90% adherence to pre-ART medications or to ART; willing to receive home visits. N = 110.	12 months.	Hunan, China.	Adherence; Viral load; CD4 count.
Improved psycho-social wellbeing	Home based nursing vs. standard care	Blank 2014 [25]	HIV-positive adults; understand spoken English; had a diagnosed serious mental illness; able to provide informed consent. N = 238.	24 months.	Philadelphia, USA.	Health related quality of life; Viral load; CD4 count.
		Hanrahan 2011 [26]	HIV-positive adults; lived within the city limits of Philadelphia; had a diagnosed serious mental illness (SMI). N = 238.	12 months.	Philadelphia, USA.	Psychiatric symptoms; Health related quality of life
		Miles 2003 [24]	African American women with HIV who were primary caregivers for at least one child under the age of 9 years. N = 109.	6 months.	USA.	Emotional distress (depression, stigma, worry); Health related quality of life
		Wang 2010 [28]	HIV-positive adults; active or previous heroin addicts; on ART at least 1 month prior to starting study. N = 116.	10 months.	Hunan, China.	Quality of life, Depression
		Williams 2014 [29]	HIV-positive adults; on ART; self-reported < 90% adherence to pre-ART medications or to ART; willing to receive home visits. N = 110.	12 months.	Hunan, China.	Depressive symptoms; social support; HIV stigma scale.