Table 1.
The relationship between expression of YAP and clinical pathological features in pancreatic cancer
| Samples (n) | YAP expression n (%) | |||||
|---|---|---|---|---|---|---|
| None | Weak | Moderate | Strong | P value◊ | ||
| Sex | 0.755 | |||||
| Male | 45 | 8(17.8) | 19(42.2) | 9(20.0) | 9(20.0) | |
| Female | 27 | 6(22.2) | 8(29.6) | 6(22.2) | 7(26.0) | |
| Age | 0.306 | |||||
| ≤55a | 37 | 9(24.3) | 16(43.2) | 6(16.2) | 6(16.2) | |
| >55 | 35 | 5(14.3) | 11(31.4) | 9(25.7) | 10(28.6) | |
| Histological grade | 0.780 | |||||
| Well | 11 | 2(18.2) | 6(54.5) | 1(9.1) | 2(18.2) | |
| Moderate | 49 | 11(22.4) | 16(32.7) | 11(22.4) | 11(22.4) | |
| Poor | 12 | 1(8.3) | 5(41.7) | 3(25.0) | 3(25.0) | |
| TNM stage (AJCC) | 0.012* | |||||
| I | 2 | 1(50.0) | 1(50.0) | 0(0) | 0(0) | |
| II | 59 | 12(20.3) | 26(44.1) | 9(15.3) | 12(20.3) | |
| III | 6 | 1(16.7) | 0(0) | 4(66.7) | 1(16.7) | |
| IV | 5 | 0(0) | 0(0) | 2(40.0) | 3(60.0) | |
| pT status | 0.135 | |||||
| T1 | 0 | 0(0) | 0(0) | 0(0) | 0(0) | |
| T2 | 8 | 1(12.5) | 3(37.5) | 2(25) | 2(25) | |
| T3 | 58 | 12(20.7) | 24(41.4) | 9(15.5) | 13(22.4) | |
| T4 | 6 | 1(16.7) | 0(0) | 4(66.7) | 1(16.7) | |
| pN status | 0.755 | |||||
| N0 | 55 | 11(20.0) | 22(40.0) | 10(18.2) | 12(21.8) | |
| N1 | 17 | 3(17.7) | 5(29.4) | 5(29.4) | 4(23.5) | |
| pM status | 0.028* | |||||
| M0 | 67 | 14(20.9) | 27(40.3) | 13(19.4) | 13(19.4) | |
| M1 | 5 | 0(0) | 0(0) | 2(40.0) | 3(60.0) | |
◊χ2 test; *Significant different, P< 0.05
aMedian age