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. 2018 Mar 27;16:29. doi: 10.1186/s12958-018-0343-0

Table 3.

ART cycle stimulation parameters and embryology outcomes

Variable Study group (n = 76) Control group (n = 93) p- value
Cycle stimulation
Total dose of Gn (IU), median (IQR) 2000 (1200, 4275) 3075 (1900, 4275) 0.03
Duration of stimulation (days), median (IQR) 10 (9, 11) 11 (9, 12) 0.08
Peak E2 concentration (pmol/l), median (IQR) 2349 (892, 4784) 1685 (1125, 3042) 0.02
Endometrial thickness on the day of hCG trigger (mm), mean ± SD 10.12 ± 1.93 10.34 ± 1.50 0.13
Patients who had oocyte retrieval 72/76 (94.74) 83/93 (89.25) 0.82
Cancelled cycles a, n (%) 4/76 (5.23) 10/93 (10.75) 0.27
Embryology outcomes
Retrieved oocytes, median (IQR) 4 (2, 5) 2 (1, 4) 0.002
ICSI cycles, n (%) 24/76 (31.58) 19/93 (20.43) 0.20
Fertilized oocytes (2PN), median (IQR) 0.80 (0.50, 0.93) 0.50 (0.33, 1.0) 0.01
Fertilization rate b, n (%) 191/253 (67.49) 191/283 (45.06) 0.001
Number of high quality embryos, median (IQR) 1 (0, 2) 0 (0, 1.75) 0.03

aIncluded women in who did not respond to stimulation and did not have oocyte retrieval

bCalculated as following: the number of total 2PN embryos divided by the number of total inseminated oocytes

E2 – estradiol; Gn – gonadotrophin; hCG – human chorionic gonadotrophin; IQR – interquartile range; LH - luteinizing hormone; P - progesterone, 2PN – two pronuclear, SD - standard deviation