Table 1.

Lung leukocyte numbers 24 hours after clodronate-liposome injection

	Vascular Ly6CHigh monocytes ×105/lungs	Vascular Ly6CLow monocytes ×105/lungs	Interstitial MHCII+ macrophages ×105/lungs	Alveolar macrophages ×105/lungs	Vascular neutrophils ×105/lungs
Control mice	4.51 (3.3–7.3)	3.15 (3.0–4.8)	0.90 (0.7–1.3)	18.8 (17.0–24.4)	5.42 (4.1–7.8)
Clodronate treated mice	1.98 (1.6–2.3)***	0.72 (0.3–1.0)**	0.70 (0.5–1.6)	18.98 (18.5–21.3)	10.0 (6.3–18.7)

Lung leukocyte numbers were quantified via flow cytometry in control (non-surgical) mice, with and without prior clodronate administration. Data were analysed by Mann–Whitney U test (median±IQR×10⁵/lungs); n=9 and 6, **p<0.01, ***p<0.001 vs control mice.