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. 2018 Mar 27;18:329. doi: 10.1186/s12885-018-4210-3

Table 1.

Patient characteristics

Characteristics NAC-CCRTa CCRT-ACb p-value
N = 79 N = 187
Age: Mean (SD) 47.9 (12.6) 51.9 (11.2) 0.011
  Min-Max
Gender: Men 56 (71%) 129 (69%) 0.880
    Women 23 (29%) 58 (31%)
WHO classification: Type I 3 (4%) 4 (2%) 0.640
               Type II 51 (65%) 126 (67%)
               Type III 25 (32%) 57 (31%)
T stage: T1 11 (14%) 53 (28%) < 0.001
     T2 15 (19%) 51 (27%)
     T3 10 (13%) 41 (22%)
     T4 43 (54%) 42 (23%)
N stage: N0 11 (14%) 24 (13%) < 0.001
     N1 9 (11%) 38 (20%)
     N2 30 (38%) 109 (58%)
     N3 29 (37%) 16 (9%)
AJCC staging: II-III 11 (14%) 132 (71%) < 0.001
         IVA-IVB 68 (86%) 55 (29%)

aNAC-CCRT: neoadjuvant chemotherapy followed by concurrent chemo-radiotherapy

bCCRT-AC: concurrent chemo-radiotherapy followed by adjuvant chemotherapy