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. 2018 Mar 27;16:30. doi: 10.1186/s12951-018-0350-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Fluorescence analysis and UV–Vis of nanoparticles: a pH-dependent (pH 5.0, 6.5, 7.4) drug release of DOX&Mn-IOSP NCs, b pH-dependent (pH 5.0, 6.5, 7.4) release of Mn-porphyrin in Mn-IOSP NCs, c fluorescence confocal micrographs of DOX&Mn-IOSP NCs (with or without modified with cRGD) and free DOX incubated in WI38 cells or A549 cells, the scale bars are 50 μm