Table 2.
Univariate relationships of angiopoietin-like 4 (ANGPLT4) levels and phospholipid transfer protein (PLTP) activity with clinical and laboratory variables in 77 subjects (41 subjects with and 36 subjects without Type 2 diabetes mellitus)
| ANGPTL4 (μg/l) | PLTP (AU) | |
|---|---|---|
| ANGPTL4 | 0.309** | |
| Age (years) | 0.261* | 0.159 |
| Systolic blood pressure (mm Hg) | 0.211* | 0.286** |
| Diastolic blood pressure (mm Hg) | 0.137 | 0.268* |
| BMI (kg/m2) | 0.368*** | 0.420*** |
| Glucose (mmol/l) | 0.341** | 0.433*** |
| HbA1c (mmol/mol) | 0.447*** | 0.390*** |
| hsCRP (mg/l) | 0.377*** | 0.373*** |
| NEFA (mmol/l) | 0.411*** | 0.304** |
| Total cholesterol (mmol/l) | −0.230* | 0.209 |
| Non-HDL cholesterol (mmol/l) | −0.209 | 0.214 |
| LDL cholesterol (mmol/l) | −0.255* | 0.178 |
| HDL cholesterol (mmol/l) | −0.106 | −0.256* |
| Triglycerides (mmol/l) | 0.127 | 0.431*** |
| ApoB (g/l) | −0.032 | 0.319** |
| ApoA-I (g/l) | −0.054 | −0.119 |
Spearman correlation coefficients. Apo apolipoprotein, ANGPTL4 angiopoietin-like 4, BMI body mass index, HbA1c glycated hemoglobin, HDL high density lipoproteins, hsCRP high sensitivity C-reactive protein, LDL low density lipoproteins, NEFA non-esterfied fatty acids, PLTP phospholipid transfer protein. LDL cholesterol was calculated in 39 T2DM subjects and in 35 non-diabetic subjects. *p < 0.05; **p < 0.01: ***p < 0.001