Table 3.
Multivariable regression analyses showing independent relationships of angiopoietin-like 4 (ANGPTL4) levels and phospholipid transfer protein (PLTP) activity with high sensitivity C-reactive protein (hsCRP), glycemia and plasma lipids in 77 subjects (41 subjects with and 36 subjects without Type 2 diabetes mellitus)
| Model A 1 ANGPTL4 |
Model A 2 ANGPTL4 |
Model B 1 PLTP activity |
Model B 2 PLTP activity |
|||||
|---|---|---|---|---|---|---|---|---|
| β | p-value | β | p-value | β | p-value | β | p-value | |
| Age | 0.173 | 0.12 | 0.209 | 0.065 | 0.094 | 0.43 | 0.119 | 0.33 |
| Sex (men vs. women) | 0.226 | 0.043 | 0.263 | 0.014 | −0.135 | 0.25 | −0.057 | 0.62 |
| T2DM | 0.088 | 0.48 | 0.376 | 0.006 | ||||
| Glucose | −0.081 | 0.51 | 0.276 | 0.034 | ||||
| hsCRP | 0.327 | 0.002 | 0.315 | 0.003 | 0.229 | 0.037 | 0.299 | 0.034 |
| NEFA | 0.360 | 0.002 | 0.374 | 0.001 | 0.020 | 0.87 | 0.105 | 0.37 |
| Total cholesterol | −0.284 | 0.009 | −0.308 | 0.005 | 0.014 | 0.90 | 0.025 | 0.83 |
| Triglycerides | 0.081 | 0.47 | 0.105 | 0.39 | 0.10 | 0.166 | 0.21 | |
Models A: ANGPTL4 as dependent variable
Models B: PLTP activity as dependent variable
Models 1: including Type 2 diabetes mellitus (T2DM) as independent variable
Models 2: including fasting glucose as independent variable
β: standardized regression coefficient, NEFA non-esterified fatty acids, T2DM Type 2 diabetes mellitus. ANGPTL4, hsCRP and triglycerides are loge transformed