Table 3.
ncRNAs and their potential target genes involved in HF cycle
| Genes | lncRNAs in cis | lncRNAs in trans | miRNAs |
|---|---|---|---|
| Transcription Factors | |||
| STAT3 | – | LOC102185409, LOC108635659, LOC108636392 | -, chi-miR-10a-5p, chi-miR-1388-3p, chi-miR-125a-3p |
| TP63 | – | LOC108634033 | -, chi-miR-378-5p |
| SOX9 | XLOC_031780 | LOC108636392, LOC102185409, LOC108635596 | -, chi-miR-125a-3p,chi-miR-30a-5p,chi-miR-141 |
| MYC | LOC102186225 | LOC108637984, LOC102185409, LOC108635656 | -, chi-miR-338-3p, chi-miR-148a-3p, chi-miR-148a-3p |
| TFAP2 | – | LOC108635596, LOC108636392, LOC108637897 | -, chi-miR-141, chi-miR-141, chi-miR-148b-5p |
| LHX2 | – | LOC108636746, LOC108636392 | -, chi-miR-130b-3p, chi-miR-296-3p and chi-miR-125a-3p |
| MSX2 | LOC102169517 | LOC108635658, LOC108635659 | -, chi-miR-1388-3p |
| FOXI3 | – | LOC108636746 | -, chi-miR-9-5p |
| HOXC13 | – | LOC108635596, LOC102188339 | -, novel_72 and chi-miR-141, chi-miR-873-5p |
| GATA3 | – | LOC108635658, LOC108636746 | -, chi-miR-1388-3p, novel_926 |
| WNT/TGFB related | |||
| WNT2 | – | LOC106502925 | -, chi-miR-29a/b-3p |
| WNT3 | – | LOC108635656, LOC108636392 | -, chi-miR-148a-3p, chi-miR-125a-3p |
| WNT4 | LOC102189078 | LOC108637984 and LOC102185409 | -, chi-miR-338-3p |
| WIF1 | – | LOC108636392 | -, chi-miR-330-3p |
| DKK1 | – | LOC108635596, LOC108636746 and LOC108636392 | -, novel_72, chi-miR-9-5p |
| TGFBR2 | – | LOC108635596 and LOC108636392 | -, chi-miR-141 |
| SAMD5 | – | LOC108635656, LOC108635596 | -, chi-miR-148a-3p, novel_72 |
| TGFB1 | – | LOC108635596, LOC108636746 | -, chi-miR-873-5p, novel_926 and chi-miR-9-5p |
| BAMBI | – | LOC108635596, LOC108636746 | -, chi-miR-141, novel_926 |
| FGF/FGFR related | |||
| FGF2 | – | LOC108635596 and LOC102188339 | -, chi-miR-873-5p |
| FGF11 | – | LOC108637983 and LOC108637984 | -, chi-miR-140-5p |
| FGF12 | – | LOC108637984, LOC102185409 | -, chi-miR-502b-5p, chi-miR-340-5p |
| FGF21 | – | LOC108635596 and LOC102188339 | -, chi-miR-873-5p |
| FGFBP1 | – | LOC108636746 | -, novel_926 and chi-miR-9-5p |
| FGFR1 | – | LOC108635596 and LOC102188339 | -, chi-miR-873-5p |
| Notch related | |||
| DLL4 | – | LOC106502925, LOC106502506, | -, novel_735, novel_1008 |
| JAG2 | – | LOC108636746, LOC108636392 | -, chi-miR-9-5p, chi-miR-330-3p |
| ADAM17 | – | LOC108635596, LOC108636392, LOC108637983 | -, novel_72, chi-miR-125a-3p, chi-miR-26a/b-5p |
| HEY1 | – | LOC102171315, LOC108637983 | -, chi-miR-101-3p, chi-miR-378-3p and chi-miR-140-5p |
| DLK2 | – | LOC108636746, LOC108636392 | -, novel_926, chi-miR-125a-3p |
| DTX1 | – | LOC108635659, LOC106502506 | -, novel_996, chi-miR-25-5p |
| DTX3L | – | LOC108635656, LOC108635596, LOC108636746 | -, chi-miR-148a-3p, chi-miR-873-5p, chi-miR-130b-3p |
| DTX4 | – | LOC106502925, LOC108636392 | -, chi-miR-29a/b-3p, novel_965 |
| SHH related | |||
| SUFU | LOC108635656, LOC108636746 | -, chi-miR-148a-3p and chi-miR-873-5p, novel_926 | |
| PRKX | LOC108636392, LOC108637983 and LOC102185409 | -, chi-miR-125a-3p, chi-miR-378-3p | |
| GLI3 | LOC108636392, LOC102171315 | -, chi-miR-24-5p, chi-miR-23b-3p | |
| BMP/TGFβ related | |||
| BMP2 | – | LOC108635659, LOC108636392 | -, novel_996, novel_965 and chi-miR-125a-3p |
| TGFB1 | – | LOC108635596, LOC108636746, LOC102188339 | -, chi-miR-873-5p, novel_926 and chi-miR-9-5p, chi-miR-873-5p |
| TGFBRAP1 | – | LOC108635656, LOC102188339 | -, chi-miR-148a-3p and chi-miR-873-5p, chi-miR-873-5p |
| TGFBR2 | – | LOC108635596 and LOC108636392, 102,171,315 | -, chi-miR-141, chi-miR-23b-3p |