Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 14;8(12):3221. doi: 10.1038/s41419-017-0078-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — a Overexpression of mutant 3′-UTR-Dlx2 in LS8 could abolish the negative effect of miR-185-5p on the expression of Amelx. b-c Overexpression of Dlx2 in MC3T3-E1 alleviated the inhibitory effect caused by miR-185-5p mimics. Alizarin Red S stain was quantified b and protein level of Ocn c was determined after treatment with STEMPRO for 21 days. d, e Inhibition of miR-185-5p could partially rescue the inhibitory effect of mutant Runx2 on expression of Amelx and Alp (1: Runx2 WT + inhibitor NC, 2: Runx2 WT + miR-185-5p inhibitor, 3: Runx2 M1 + inhibitor NC, 4: Runx2 M1 + miR-185-5p inhibitor, 5: Runx2 M2 + inhibitor NC, 6: Runx2 M2 + miR-185-5p inhibitor, 7: Runx2 M3 + inhibitor NC, 8: Runx2 M3 + miR-185-5p inhibitor)