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. 2017 Dec 13;8(12):3212. doi: 10.1038/s41419-017-0017-4

Fig. 4. σ-1R is involved in ERS induced by SiO2.

Fig. 4

a Representative western blot depicting the effect of BD1047 on PERK phosphorylation. b Densitometric analysis of PERK and p-PERK protein expression levels from five independent experiments; *p < 0.05 vs the control group; # p < 0.05 vs the SiO2 group. c Representative western blot depicting the effect of BD1047 on eIF2α phosphorylation. d Densitometric analysis of eIF2α and p-eIF2α protein expression levels from five independent experiments; *p < 0.05 vs the control group; # p < 0.05 vs the SiO2 group. e Representative western blot depicting the effect of BD1047 on CHOP, ATF6α and IRE1α protein expression. Densitometric analysis of CHOP f, ATF6α g, and IRE1α h protein expression levels from five independent experiments; *p < 0.05 vs the control group; # p < 0.05 vs the SiO2 group