Figure 2.

ZWINT was highly expressed in lung cancer patients. (A and B) Real-time PCR analysis of ZWINT expression in 40 lung cancer specimens and adjacent nontumor tissues. (C) Analysis of ZWINT expression in normal lung and different histological subtypes of lung cancer in GSE30219. (D) Oncomine data showing ZWINT expression in lung cancer. (E and F) Analysis of ZWINT expression in normal lung and stage IA lung cancer tissue in GSE31210 and GSE30219. (G) Analysis of ZWINT expression in EGFR-mutated and EGFR-non-mutated lung cancer tissue. β-Actin was used as the internal control for real-time PCR. Experiments were done in triplicate. *P<0.05; **P<0.01.

Abbreviations: ZWINT, ZW10 interacting protein; SCLC, small-cell lung cancer; ADC, adenocarcinoma; SCC, squamous cell carcinoma; LCC, large-cell carcinoma; LCNE, large-cell neuroendocrine tumor; BAS, basaloid; CARCI, carcinoid tumor.