Fig. 6.

The effect of coverage, number of samples, and number of vertices on performance of AncesTree and PASTRI. For every combination of parameters, we generate 50 trees. Here we report the proportion of ancestral relationships that were correctly recovered. Overall, PASTRI has higher average performance for all sets of parameters, but the magnitude of this effect differs. (a) As the coverage increases, and uncertainty in variant allele frequencies decreases, PASTRI’s accuracy increases. AncesTree’s accuracy increases initially, but declines at the highest coverages. (b) Similarly, as the number of samples increases and the problem becomes more constrained, PASTRI’s accuracy increases, while AncesTree’s accuracy peaks with four samples, and then declines. (c) As the number of vertices in the tree increase, both AncesTree and PASTRI see a similar moderate decline in performance, although PASTRI consistently outperforms AncesTree