Table 1.
Cell lines | Potential novel predictive TF of top 5% importance (in PEP-Motif but not in TargetFinder) |
---|---|
2 (E) | (PRGR, ANDR, GCR), BHE23, (TBX4,TBR1,TBX21), |
CEBPE, EGR3, ENOA,(EVX1, FOXG1,FOXL1), FOXO1, | |
HAND1, HBP1, HOXA1, MCR, (NFAT5,NFAC3), STAT6, | |
(NR1I2, NR1I3), RHXF1, SMAD3, SOX10, SOX4, | |
BRAC, TEAD3, ZNF713 | |
3 (E) | EHF, ZSC16 |
2 (P) | AP2D, (KLF4, KLF1,KLF3), NKX32, PLAG1 |
3 (P) | (HOXD8, POU5F1B, POU2F2, POU3F3), (MNT,SPIC) |
Cell lines | Potential novel predictive TF of top 10% importance (in PEP-Motif but not in TargetFinder) |
---|---|
3 (E) | BHE23, ERR2, ENOA, EOMES, FEV, GCM1, |
(HSF1, HSF2, HOXB2, HSF4), HOXA1, (KLF3, KLF1, KLF4), | |
MCR, MITF, MYOD1, (RORG, RORA, NR1D1), | |
(NR1I2, NR1I3), SMAD3, TEAD3, TF7L2, ZBT18, ZNF713 | |
4 (E) | (ANDR, PRGR, GCR), EGR3, ETV5, HAND1, ZSC16 |
5 (E) | EHF |
3 (P) | (HOXD8, POU5F1B, POU2F2, POU3F3), PLAG1 |
4 (P) | (KLF4, KLF1, KLF3), (MNT, SPIC) |
Note: Each TF is represented by one or multiple motifs. If the corresponding motif is associated with a motif cluster, all members of the cluster are displayed and the motif reaching the specified importance level is in italic. ‘E’ represents enhancer regions and ‘P’ represents promoter regions. The row name represents the exact number of cell lines where the motif reaches the specified importance level, e.g. ‘2 (E)’ denotes that the feature in the enhancer region has top 5% importance in exactly two cell lines.