Table 2.
P. vivax resistance-associated molecular marker prevalence
| Codon | % of mutations | Mutation | Protein change |
|---|---|---|---|
| mdr1 | |||
| 2873 | 62 | ACG>ATG | T958M |
| 2949 | 38 | TTT>TTA | F983L |
| 2982 | 54 | TTC>CTC | D994E |
| 3064 | 2 | CTA>TTA | L1022 |
| 3208 | 2 | TTC>CTC | F1070L |
| dhfr | |||
| 45 | 12.2 | GCA>GCG | A15 |
| 57 | 12.2 | GTC>GTT | V19 |
| 149 | 2.44 | AAC>ATC | N50I |
| 171 | 2.44 | TTC>TTG | F57L |
| 173 | 31.7 | AGC>AAG | S58K |
| 174 | 97.5 | AGC>AGG/AGA | S58R |
| 207 | 82.9 | TAT>TAC | Y69 |
| 350 | 97.6 | AGC>AAC | S117N |
| 517 | 4.88 | ATT>CTT | I173L |
| 524 | 4.88 | GGA>GAA | G175E |
| dhps | |||
| 1145 | 8.3 | TCC>TGC | S382C |
| 1148 | 41.6 | GCC>GGC | A383G |
| 1385 | 2 | AAG>AGAG | K462R |