Table 1.
CRT group (n = 16) | TAU group (n = 15) | |||||
---|---|---|---|---|---|---|
Mean | SD | Mean | SD | t or χ2 | P | |
Sex (male/female) | 10/6 | 9/6 | χ2 = 0.02 | 0.59 | ||
Age (years) | 36.1 | 7.7 | 37.4 | 11.0 | t = − 0.39 | 0.70 |
Handedness (right/left) | 16/0 | 13/2 | χ2 = 2.28 | 0.23 | ||
Years of education | 14.3 | 2.4 | 13.0 | 2.0 | t = 1.69 | 0.10 |
Years from onset of schizophrenia | 12.1 | 7.8 | 13.9 | 13.2 | t = −0.47 | 0.65 |
Number of hospitalizations | 1.0 | 1.2 | 2.1 | 1.9 | t = − 2.00 | 0.056 |
JART | 102.6 | 11.8 | 97.8 | 12.2 | t = 1.10 | 0.28 |
Drugs | ||||||
Mean dosage of antipsychoticsa | 440.3 | 265.1 | 680.3 | 530.9 | t = −1.61 | 0.12 |
Mean dosage of anticholinergicsb | 0.75 | 1.65 | 1.30 | 1.51 | t = −0.97 | 0.34 |
PANSS | ||||||
Positive symptoms | 14.8 | 4.9 | 14.3 | 4.2 | t = 0.26 | 0.80 |
Negative symptoms | 20.7 | 4.4 | 20.6 | 7.2 | t = 0.04 | 0.97 |
General psychopathology | 39.6 | 7.8 | 41.5 | 10.5 | t = −0.57 | 0.57 |
LASMI | ||||||
Interpersonal relations | 11.1 | 3.9 | 11.5 | 7.9 | t = −2.13 | 0.83 |
Work skills | 10.6 | 3.4 | 12.6 | 5.7 | t = −1.22 | 0.23 |
BACS (z-score) | ||||||
Verbal memory | −1.8 | 1.0 | −2.0 | 1.1 | t = 0.56 | 0.58 |
Working memory | −1.3 | 1.2 | −1.3 | 1.2 | t = −0.18 | 0.86 |
Motor speed | −2.4 | 1.4 | −2.8 | 1.6 | t = 0.76 | 0.45 |
Verbal fluency | −1.4 | 0.8 | −0.9 | 0.8 | t = − 1.68 | 0.10 |
Attention and speed of information processing | −1.6 | 0.8 | −2.1 | 0.9 | t = 1.45 | 0.16 |
Executive functions | −0.4 | 2.3 | −1.1 | 1.6 | t = 0.97 | 0.34 |
Composite score | −1.5 | 0.9 | −1.7 | 0.9 | t = 0.63 | 0.53 |
Abbreviations: BACS Brief Assessment of Cognition in Schizophrenia, CRT cognitive remediation therapy, JART National Adult Reading Test, Japanese Version, LASMI Life Assessment Scale for the Mentally Ill, PANSS Positive and Negative Syndrome Scale, SD standard deviation, TAU treatment as usual
aChlorpromazine-equivalent dose (mg/day)
bBiperiden-equivalent dose (mg/day)