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. 2018 Mar 27;15(3):e1002540. doi: 10.1371/journal.pmed.1002540

Table 1. Characteristics by patient-rated health.

Characteristic Total (N = 10,575) Worse patient-rated health* (N = 5,430) Better patient-rated health* (N = 5,145) Missing (%)
Patient and environmental factors
Age, years 74 [65–81] 75 [67–81] 72 [64–80]
Women 3,473 (32.8) 1,957 (36.0) 1,516 (29.5)
Single 3,958 (38.6) 2,205 (41.7) 1,753 (35.3) 3.1
Body mass index 26.7 [24–30] 26.7 [24–30] 26.7 [24–30] 4.6
Current smoker 1,202 (12.6) 655 (13.5) 547 (11.7) 10.0
Haemoglobin, g/l 134 ± 17 133 ± 17 136 ± 16 0.03
Ejection fraction 8.5
    <40% 6,031 (62.3) 3,078 (62.2) 2,953 (62.5)
    40%–49% 2,126 (22.0) 1,034 (20.9) 1,092 (23.1)
    ≥50% 1,517 (15.7) 835 (16.9) 682 (14.4)
Heart failure ≥ 6 months 5,161 (49.1) 2,873 (53.2) 2,288 (44.7) 0.6
Heart rate 72.4 ± 14.7 73.3 ± 14.8 71.5 ± 14.6 0.01
Beta blocker 9,330 (88.5) 4,788 (88.6) 4,452 (88.5) 0.4
ACEi or ARB 9,520 (90.4) 4,812 (89.1) 4,708 (91.7) 0.4
Diuretic 8,138 (77.4) 4,446 (82.4) 3,692 (72.1) 0.6
Device 1,440 (13.8) 772 (14.4) 668 (13.1) 1.2
Cardiology care 5,506 (59.5) 2,731 (57.3) 2,775 (61.7) 12.5
Inpatient 2,746 (26.0) 1,466 (27.0) 1,280 (24.9)
Comorbidities
Ischemic heart disease 5,418 (53.9) 2,696 (52.4) 2,181 (44.5) 5.0
Atrial fibrillation 5,064 (48.1) 2,739 (50.7) 3,325 (45.4) 0.5
Hypertension 5,311 (51.5) 2,745 (52.1) 2,566 (51.0) 2.5
Dilated cardiomyopathy 1,599 (15.7) 750 (14.4) 849 (17.1) 3.5
Valve disease 603 (5.8) 322 (6.0) 281 (5.5) 1.3
Diabetes 2,518 (23.9) 1,447 (26.8) 1,071 (20.9) 0.5
Chronic obstructive pulmonary disease 1,813 (17.4) 1,101 (20.7) 712 (14.0) 1.7
Chronic kidney disease** 4,646 (43.9) 2,619 (48.2) 2,027 (39.4)
Symptoms
Shortness of breath 7.4
    Any 8,354 (85.3) 4,623 (92.7) 3,731 (77.7)
    Marked or severe 3,475 (35.0) 2,528 (50.7) 947 (19.7)
Fatigue 7.5
    Any 8,281 (84.6) 4,648 (93.1) 3,633 (75.8)
    Marked or severe 3,400 (34.7) 2,494 (49.9) 906 (18.9)
Pain (any) 5,065 (51.9) 3,206 (64.4) 1,859 (38.9) 7.8
Anxiety or depression (any) 4,336 (44.6) 2,932 (59.2) 1,404 (29.4) 8.0
Functional limitations (usual activities) 3,636 (37.2) 2,619 (52.6) 1,017 (21.3) 7.7
Patient-rated health 62.6 ± 19.9 47.2 ± 14.0 78.8 ± 9.7

Data are expressed as frequency (%), mean ± standard deviation, or median [interquartile range] (for variables with skewed distribution).

*Patient-rated health was determined by the EuroQol visual analogue scale. Patients rated their health from 0 (worst imaginable health state) to 100 (best imaginable health state). We dichotomised this at the mean value (<63, ≥63) to describe ‘worse’ and ‘better’ patient-rated health for our sample.

**Defined by estimated glomerular filtration rate < 60 ml/min/1.73 m2.

ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker.